i(3)(q10) in non-Hodgkin's lymphoma (NHL)

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dc.contributor.author Zamecnikova, Adriana -
dc.date.accessioned 2019-12-03T07:28:08Z
dc.date.available 2019-12-03T07:28:08Z
dc.date.issued 2019 -
dc.identifier.citation Adriana, Zamecnikova. i(3)(q10) in non-Hodgkin's lymphoma (NHL). Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2019, 11, p. 333-335 -
dc.identifier.issn 1768-3262
dc.identifier.uri http://hdl.handle.net/2042/70608
dc.description.abstract Partial or complete chromosome 3 gains resulting from the presence of trisomy 3, unbalanced translocation or isochromosome formation has been observed in different types of non-Hodgkin's lymphomas (NHL). Among them, the isochromosome of the long arm of chromosome 3 is a relatively rare chromosome aberration, associated mainly with B-cell NHL. However, its occurrence is not restricted to lymphomas, as the detection of +i(3)(q10) is considered a specific marker of polyclonal B-cell lymphocytosis with binucleated lymphocytes (PPBL) associated with an increase frequency of chromosome 3 instability as well as it may also be found in myeloid malignancies. en
dc.language.iso en -
dc.publisher ARMGHM - Atlas Génétique des Cancers -
dc.relation Atlas of Genetics and Cytogenetics in Oncology and Haematology ; http://AtlasGeneticsOncology.org/Anomalies/i3q10ID2115.html -
dc.relation.ispartofseries Atlas of Genetics and Cytogenetics in Oncology and Haematology en
dc.rights Open access resource - terms and conditions : http://irevues.inist.fr/utilisation -
dc.subject chromosome 3 en
dc.subject B-cell lymphomas en
dc.subject T-cell lymphomas en
dc.subject.classification Leukaemia Section en
dc.subject.mesh Antibiotics, Antineoplastic/*pharmacology en
dc.subject.mesh Apoptosis/drug effects en
dc.subject.mesh Cadherins/*genetics en
dc.subject.mesh Carcinogenesis/genetics en
dc.subject.mesh Cell Line, Tumor en
dc.subject.mesh Cell Survival/drug effects en
dc.subject.mesh *DNA Methylation en
dc.subject.mesh DNA Modification Methylases/antagonists & inhibitors en
dc.subject.mesh Down-Regulation/drug effects en
dc.subject.mesh Doxorubicin/*pharmacology en
dc.subject.mesh Gene Expression Regulation, Neoplastic/drug effects en
dc.subject.mesh Humans en
dc.subject.mesh Karyotype en
dc.subject.mesh Lymphoma, Non-Hodgkin/*genetics/pathology en
dc.subject.mesh Multiple Myeloma/*genetics/pathology en
dc.subject.mesh *Promoter Regions, Genetic en
dc.subject.mesh Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization en
dc.subject.mesh Adult en
dc.subject.mesh Aged en
dc.subject.mesh Aged, 80 and over en
dc.subject.mesh Biomarkers, Tumor/genetics/metabolism en
dc.title i(3)(q10) in non-Hodgkin's lymphoma (NHL) en
dc.type Article -
dc.contributor.affiliation Kuwait Cancer Control Center, Kuwait -
dc.identifier.doi https://doi.org/10.4267/2042/70608


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