HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)

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Title: HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)
Author: Erdem, Murat; Özgül, Ibrahim; Erson-Bensan, Ayse Elif
Abstract: Heterogeneous nuclear ribonucleoprotein (HNRNPA1) gene maps to chromosome 12, plus strand and has 13 exons and 12 introns. There are three reported transcripts due to the alternative splicing. HNRNPA1 is one of the most abundant and ubiquitously expressed nuclear proteins. HNRNPA1 is a member of RNA-binding protein family comprising of 20 members in humans (Dreyfuss, 1993; Pinol-Roma, Choi, Matunis, & Dreyfuss, 1988). HNRNPA1 has diverse roles in RNA splicing, telomere length maintenance, miRNA maturation and mRNA transport from nucleus to cytoplasm.
Subject: HNRNPA1; RNA-binding protein; RNA splicing; telomere length maintenance; miRNA maturation; mRNA transport; Genes Section; Animals; Biomarkers, Tumor/*genetics; Carcinogenesis/genetics; Cell Line, Tumor; Cell Movement/genetics; Cell Proliferation/genetics; Epithelial-Mesenchymal Transition/*genetics; Female; Gene Expression Regulation, Neoplastic; Heterogeneous Nuclear Ribonucleoprotein A1/*genetics; Humans; Male; Mice; Neoplasm Invasiveness/genetics/pathology; Stomach Neoplasms/*genetics/pathology; Xenograft Model Antitumor Assays; Adult; Aged; Aged, 80 and over
Publisher: ARMGHM - Atlas Génétique des Cancers
Date: 2019

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