del(7)(p11-15) solely

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Title: del(7)(p11-15) solely
Author: Zamecnikova, Adriana
Abstract: Complete or partial loss of chromosome 7 is a recurrent cytogenetic abnormality that may be observed in both de novo and therapy-related hematopoietic disorders. It predominantly presents as monosomy 7 or deletion of the long arm of chromosome 7, often associated with an unfavorable prognosis. Deletions of the short arm of chromosome 7, originated from either a terminal or an interstitial deletion are less frequent and their pathological significance is less well characterized.
Subject: Monosomy 7; 7p deletions; gene deletions; tumor suppressor genes; Leukaemia Section
Publisher: ARMGHM - Atlas Génétique des Cancers
Date: 2018

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