PCSK1 (proprotein convertase subtilisin/kexin type 1)

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URI: http://hdl.handle.net/2042/68910  |   DOI : https://doi.org/10.4267/2042/68910
Title: PCSK1 (proprotein convertase subtilisin/kexin type 1)
Author: Demoures, Béatrice; Siegfried, Géraldine; Khatib, Abdel-Majid
Abstract: PCSK1 is a serine protease involved in the proteolytic processing of a variety of protein precursors mainly neuropeptides and prohormones. In 1991, PC1/3; also known as PCSK1, PC1, PC3, and SPC3 was identified at the same time by two laboratories separately. The human and mouse PCSK1 genes are localized on chromosomes 5 and 13, respectively. The cleavage of these protein precursors is required for the mediation of their functions including the regulation of glucose homeostasis and food intake.
Subject: PCSK1; PC1; endocrine disorders; cancer; chromosome 5; Genes Section
Publisher: ARMGHM - Atlas Génétique des Cancers
Date: 2018

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