SNW1 (SNW domain containing 1)

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Title: SNW1 (SNW domain containing 1)
Author: Olgun, Cagla Ece; Muyan, Mesut
Abstract: SNW1 is a spliceosomal component and transcriptional co-regulator that provides a modulatory coupling of transcription initiation and splicing. SNW1 appears to be an essential cancer cell survival factor by co-transcriptionally regulating mRNA splicing of proteins involved in cell cycle checkpoints... a co-regulator, SNW1 is shown to attune the activity of a number of transcription factors, including nuclear hormone receptors as well as CBF1, Smad2/3, and MyoD by modulating a transition step bet
Subject: SNW1; cancer; transcription regulation; Genes Section; Aged; Biomarkers, Tumor/*analysis; *Cell Proliferation/physiology; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen/biosynthesis; Lung Neoplasms/metabolism/mortality/*pathology; Male; Mesothelioma/metabolism/mortality/*pathology; Middle Aged; Mitotic Index; Phosphoric Monoester Hydrolases/analysis/*biosynthesis; Pleural Neoplasms/metabolism/mortality/*pathology; Prognosis
Publisher: ARMGHM - Atlas Génétique des Cancers
Date: 2018

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