dup (11q) in myeloid malignancies

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URI: http://hdl.handle.net/2042/68540  |   DOI : https://doi.org/10.4267/2042/68540
Title: dup (11q) in myeloid malignancies
Author: Zamecnikova, Adriana; Al Bahar, Soad
Abstract: Partial gain of the long arm of chromosome 11, containing the unrearranged mixed lineage leukaemia (MLL) gene (KMT2A; lysine (K)-specific methyltransferase 2A) is a rare but recurrent anomaly in myeloid malignancies, and is often associated with an older age and a higly complex karyotype.
Subject: gene amplification; intrachromosomal KMT2A duplication; karyotype complexity; acute myeloid leukemia; Leukaemia Section
Publisher: ARMGHM - Atlas Génétique des Cancers
Date: 2017

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