Review on t(3;9)(p13;q34.1) FOXP1/ABL1, with data on clinics, and the genes involved....

Review on Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis...

Review on t(1;22)(p36;q11) IGL/PRDM16 translocations, with data on clinics, and the genes involved....

Although T-cell/histiocyte rich large B-cell lymphoma (THRLBCL) is an aggressive diffuse large B-cell lymphoma (DLBCL), its morphology can resemble nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). These two entities are closely related: both diseases contain neoplastic cells with similar morphologic and immunophenotypic features but differ with respect to their architecture and the nature of the reactive background. Due to the overlapping features between THRLBCL and NLPHL, it is sometimes impossible to distinguish these two entities; thus, ""grey zone"" lymphoma is used to define some of those cases. Because of the morphologic and immunophenotypic similarities between THRLBCL and NLPHL, it is possible that these two entities may represent different stages of the same disease. A possible biological relation of THRLBCL with NLPHL has been suggested. Overlapping recurrent genetic abnormalities (gain of 4q and loss of 19p) might be the genetic link between THRLBCL and NLPHL....

Complete or partial monosomies of the long arm of chromosome 5 and/or 17p are common findings in myeloid malignancies, particularly in therapy-relatedmyeloid disorders. They usually result from interstitial or terminal deletions and less frequently from unbalanced rearrangements such as dicentric chromosomes. One of the recurring unbalanced translocation in myeloid malignancies is the unbalanced dicentric translocation dic(5;17)(q11-14;p11-13) that results in complete or partial monosomy for the long arm of chromosome 5 and the short arm of chromosome 17....