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Showing 7 out of a total of 7 results for community: Atlas of Genetics and Cytogenetics in Oncology and Haematology - 2017. (0.003 seconds)
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(ARMGHM - Atlas Génétique des Cancers, 2017)Although T-cell/histiocyte rich large B-cell lymphoma (THRLBCL) is an aggressive diffuse large B-cell lymphoma (DLBCL), its morphology can resemble nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). These two entities are closely related: both diseases contain neoplastic cells with similar morphologic and immunophenotypic features but differ with respect to their architecture and the nature of the reactive background. Due to the overlapping features between THRLBCL and NLPHL, it is sometimes impossible to distinguish these two entities; thus, ""grey zone"" lymphoma is used to define some of those cases. Because of the morphologic and immunophenotypic similarities between THRLBCL and NLPHL, it is possible that these two entities may represent different stages of the same disease. A possible biological relation of THRLBCL with NLPHL has been suggested. Overlapping recurrent genetic abnormalities (gain of 4q and loss of 19p) might be the genetic link between THRLBCL and NLPHL....
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(ARMGHM - Atlas Génétique des Cancers, 2017)Over the past 50 years, a relevant progress has been made toward our understanding of classical Hodgkin lymphoma pathology and cell biology. Histologic classification evolved through different systems to the 2008 World. Nodular sclerosis is a subtype of classical Hodgkin lymphoma characterized by sclerosis, diagnostic Hodgkin and Reed-Sternberg cells and other tumour cells displaying a ""lacunar"" type morphology. The architectural pattern consists of grouped lacunar cells in lymphoid nodules surrounded by collagen bands. Nodular sclerosis classical Hodgkin lymphoma may have a cellular proliferation of fibroblasts, in addition to the sclerotic component. The amount of sclerosis varies markedly from case to case, from ample sclerosis (total sclerosis phase of nodular sclerosis) to a paucity of collagen associated with abundance of lacunar cells (cellular phase of nodular sclerosis) Health Organization classification, upgraded in 2016...
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(ARMGHM - Atlas Génétique des Cancers, 2017)Review on Anaplastic large cell lymphoma, ALK-negative, with data on clinics, and the genes involved....
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(ARMGHM - Atlas Génétique des Cancers, 2017)This CARD addresses the following questions: 1) how should in situ follicular neoplasia be defined and diagnosed? and 2) how should people/patients with in situ follicular neoplasia be managed?...
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(ARMGHM - Atlas Génétique des Cancers, 2017)The 2016 revised World Health Organization (WHO) classification includes several provisional borderline categories for lymphoma cases that do not clearly fit into one entity, such as B-cell lymphoma, unclassifiable (BCLU), with features intermediate between diffuse large B-cell lymphoma (DLBCL) and classical Hodgkin lymphoma (cHL). This CARD focuses on lymphomas that are intermediate between DLBCL of the primary mediastinal large B-cell lymphoma (PMLBCL) type and cHL....
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(ARMGHM - Atlas Génétique des Cancers, 2017)Over the past 50 years, a relevant progress has been made toward our understanding of classical Hodgkin lymphoma pathology and cell biology. Histologic classification evolved through different systems to the 2008 World Health Organization classification, upgraded in 2016. Mixed cellularity is a subtype of classical Hodgkin lymphoma characterized by diagnostic Hodgkin-Reed Sternberg cells in a mixed inflammatory back-ground without sclerosis. Mononuclear Hodgkin cells can be present. The mixed cellular background is considered the hallmark of the Mixed cellularity classical Hodgkin lymphoma subtype. In particular, heterogeneous constituents including admixed eosinophils plasma cells, histiocytes and small lymphocytes are usually found. The composition of this background varies greatly....
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(ARMGHM - Atlas Génétique des Cancers, 2017)
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