TP53 (Tumour protein p53 (Li-Fraumeni syndrome))

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Title: TP53 (Tumour protein p53 (Li-Fraumeni syndrome))
Author: Soussi, Thierry
Abstract: Review on TP53, with data on DNA, on the protein encoded, and where the gene is implicated.
Subject: TP53; TP53 pathway; stress; homeostasis; apoptosis; growth arrest; senescence; DNA repair; warburg effect; autophagy; stem cell maintenance; skin cancer; melanoma; lung cancer; breast cancer; colorectal cancer; prostate cancer; gastric cancer; hepatocellular carcinoma; cervical cancer; esophageal carcinoma; bladder cancer; pancreatic cancer; head and neck squamous cell carcinoma; ovarian carcinoma; osteosarcoma; glioblastoma; chronic lymphocytic leukaemia; follicular lymphoma; diffuse large b-cell lymphoma; burkitt lymphoma; myelodysplastic syndromes; acute myeloid leukaemia; Li-Fraumeni syndrome; Genes Section; *Cell Death; *Cell Survival; Humans; Tumor Suppressor Protein p53/*metabolism; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Li-Fraumeni Syndrome/*epidemiology/genetics/pathology; Magnetic Resonance Imaging; Neoplasms/*diagnostic imaging/*epidemiology/genetics; Radiography; Risk Management; Tumor Suppressor Protein p53/*genetics; Animals; Aza Compounds/metabolism; Bridged Bicyclo Compounds, Heterocyclic/metabolism; Humans; Maleimides/metabolism; Mutation/genetics; Phenotype
Publisher: ARMGHM - Atlas Génétique des Cancers
Date: 2016

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