Effects of Ox-LDL on Macrophages NAD(P)H Autofluorescence Changes by Two-photon Microscopy

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dc.contributor.author Lin, Ching-Ting
dc.contributor.author Tien, En-Kuang
dc.contributor.author Lee, Szu-Yuan
dc.contributor.author Lu, Long-Sheng
dc.contributor.author Wu, Chau-Chung
dc.contributor.author Dong, Chen-Yuan
dc.contributor.author Lin, Chii-Wann
dc.date.accessioned 2006-12-07T08:22:20Z
dc.date.available 2006-12-07T08:22:20Z
dc.date.issued 2006 en_US
dc.identifier.citation European Nano Systems 2005, Paris, France, 14-16 December 2005 en_US
dc.identifier.isbn 2-916187-02-2 en_US
dc.identifier.other handle TIMA 2243/ENS2005_1022 en_US
dc.identifier.uri http://hdl.handle.net/2042/6271
dc.description.abstract Ox-LDL uptakes by macrophage play a critical role in the happening of atherosclerosis. Because of its low damage on observed cells and better signal-to- background ratio, two-photon excitation fluorescence microscopy is used to observe NAD(P)H autofluorescence of macrophage under difference cultured conditions- bare cover glass, coated with fibronectin or poly-D-lysine. The results show that the optimal condition is fibronectin coated surface, on which, macrophages profile can be clearly identified on NAD(P)H autofluorescence images collected by two-photon microscopy. Moreover, different morphology and intensities of autofluorescence under different conditions were observed as well. In the future, effects of ox-LDL on macrophages will be investigated by purposed system to research etiology of atherosclerosis. en_US
dc.format.extent 794711 bytes
dc.format.mimetype application/pdf
dc.language.iso EN en_US
dc.publisher TIMA Editions , Grenoble, France en_US
dc.rights http://irevues.inist.fr/utilisation en_US
dc.source European Nano Systems 2005, Paris, France, 14-16 December 2005 en_US
dc.subject Two-photon microscopy, atherosclerosis, ox-LDL, autofluorescence en_US
dc.title Effects of Ox-LDL on Macrophages NAD(P)H Autofluorescence Changes by Two-photon Microscopy en_US
dc.type Conference proceeding en_US
dc.contributor.affiliation Institute of Biomedical Engineering [Taiwan]
dc.contributor.affiliation Graduate Institute Pharmacology [Taiwan]
dc.contributor.affiliation Departments of Internal Medicine and Primary Care Medicine [Taiwan]
dc.contributor.affiliation Department of Internal Medicine Eda Hospital [Kaoshiung]
dc.contributor.affiliation Department of Physics [Taiwan]


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