ANKHD1 (ankyrin repeat and KH domain containing 1)

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Title: ANKHD1 (ankyrin repeat and KH domain containing 1)
Author: Machado-Neto, Joao Agostinho; Traina, Fabiola
Abstract: ANKHD1 is differentially expressed in human cancers, and potentially regulates multiple cellular functions and participates as a scaffold for protein-protein interactions through its ankyrin-repeat domains. Recently, studies have indicated that ANKHD1 is involved in the regulation of important biological process that participate in the malignant phenotype, including cell cycle progression, proliferation, clonogenicity and migration. The present review on ANKHD1 contains data on DNA/RNA, protein encoded and where the gene is implicated.
Subject: ANKHD1; Cell cycle; Cell proliferation; Migration; Cancer; Genes Section; Amino Acid Sequence; Animals; Cell Movement/*genetics; Cell Proliferation/*genetics; Female; Gene Silencing; HEK293 Cells; Humans; Jurkat Cells; Leukemia/genetics/metabolism/*pathology; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Sequence Data; RNA-Binding Proteins/*genetics; Stathmin/antagonists & inhibitors/*metabolism; U937 Cells; Active Transport, Cell Nucleus/drug effects; Animals; Blotting, Western; Cell Line, Tumor
Publisher: Jean-Loup Huret (Editor-in-Chief)
Date: 2016

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