Unbalanced whole-arm translocation der(1;13) in hematologic malignancies

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URI: http://hdl.handle.net/2042/62510  |   DOI : https://doi.org/10.4267/2042/62510
Title: Unbalanced whole-arm translocation der(1;13) in hematologic malignancies
Author: Zamecnikova, Adriana; Al Bahar, Soad
Abstract: Whole-arm chromosome translocations involving the long arm of chromosome 1 are nonrandom aberrations in hematologic malignancies that commonly involve acrocentric chromosomes. Among them, unbalanced whole-arm translocations between chromosomes 1 and 13 are relatively rare cytogenetic aberrations and has been reported in both lymphoid and myeloid neoplasms.
Subject: chromosome 1; chromosome 13; translocation; hematologic malignancies; Leukaemia Section; Bone Marrow Cells/metabolism/pathology; *Chromosome Deletion; Chromosomes, Human, Pair 1/*genetics; Chromosomes, Human, Pair 17/*genetics; Cytogenetic Analysis; Disease Progression; Humans; In Situ Hybridization, Fluorescence; Interspersed Repetitive Sequences; Karyotype; Multiple Myeloma/*genetics/pathology; Risk; *Translocation, Genetic; Adolescent; Adult; Bone Marrow/physiology; Child; Child, Preschool; Core Binding Factor Alpha 2 Subunit/*genetics; Fanconi Anemia/complications/*genetics; Fem
Publisher: Jean-Loup Huret (Editor-in-Chief)
Date: 2016

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