FAS (Fas cell surface death receptor)

Show full item record

Files in this item

PDF 11-2014-FASID207ch10q23.pdf 455.9Kb

Pour citer ce document :
URI:http://hdl.handle.net/2042/62486  |   DOI : 10.4267/2042/62486
Title: FAS (Fas cell surface death receptor)
Author:Sanséau, Doriane; Legembre, Patrick
Abstract:CD95 (also known as Fas) is a death receptor that belongs to the TNF-receptor superfamily. Expressed at the cell surface as a homotrimer, this receptor implements both apoptotic and non-apoptotic signalling pathways. While the apoptotic signalling pathway is involved in tumor surveillance, peripheral tolerance and immune homeostasis (Strasser et al., 2009), its non-apoptotic cues seem to promote oncogenesis (Chen et al., 2010; Hoogwater et al., 2010; Kleber et al., 2010; Malleter et al., 2013; Steller et al., 2011).
Subject:CD95; Fas; apoptosis; inflammation; auto-immunity; metastasis; Genes Section
Publisher:Jean-Loup Huret (Editor-in-Chief)
Date:2015

This item appears in the following Collection(s)

Show full item record





Advanced Search