CHD6 (chromodomain helicase DNA binding protein 6)

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URI:  |   DOI : 10.4267/2042/62143
Title: CHD6 (chromodomain helicase DNA binding protein 6)
Author:Lathrop, Melissa; Rhodes, C Harker; Fiering, Steve
Abstract:CHD6 is a chromatin remodeling protein characterized to play a role in transcriptional repression of genes and viruses. It occurs in a nuclear location as a component of a larger complex which associates with RNA Pol II. Mutations in CHD6 are associated with motor coordination defects, and development of cancers following substitutions and translocations.
Subject:Chromodomain Helicase DNA Binding protein 6 - CHD6; Genes Section; Humans; FeMice; Aged; Two-Hybrid System Techniques; Protein Binding; DNA Helicases/*metabolism; *Chromosomes, Human, Pair 20; Chromatin Assembly and Disassembly; Adult; Viral Proteins/*metabolism; *Translocation, Genetic; RNA Interference; Protein Structure, Tertiary; Phylogeny; Nerve Tissue Proteins/*metabolism; *Mutation; Molecular Sequence Data; Middle Aged
Publisher:Jean-Loup Huret (Editor-in-Chief)

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