ROS1 (ROS proto-oncogene 1 , receptor tyrosine kinase)

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URI:  |   DOI : 10.4267/2042/62121
Title: ROS1 (ROS proto-oncogene 1 , receptor tyrosine kinase)
Author:Klempner, Samuel J; Ou, Sai-Hong
Abstract:ROS1 is proto-oncogene encoding a type I integral membrane protein with receptor tyrosine kinase (RTK) activity. ROS1 is a member of the insulin receptor family and is involved in downstream signalling processes involved in cell growth and differentiation.
Subject:ROS1; tyrosine kinase; insulin receptor family; cell growth and differentiation; cancer; Genes Section; Humans; 3T3 Cells; Animals; Proto-Oncogene Proteins/*genetics; Protein-Tyrosine Kinases/*genetics; Middle Aged; Mice; Aged; Adult; Mutation; In Situ Hybridization; Fluorescence; Cell Line; Tumor; Aged; 80 and over; Neoplasm Staging; Molecular Sequence Data; *Gene Rearrangement; Cell Proliferation/drug effects; *Translocation; Genetic; Signal Transduction
Publisher:Jean-Loup Huret (Editor-in-Chief)

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