GRPR (Gastrin-Releasing Peptide Receptor)

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Title: GRPR (Gastrin-Releasing Peptide Receptor)
Author: Moody, TW
Description: Bombesin (BB) and gastrin-releasing peptide (GRP) bind with high affinity to the GRP-receptor (GRP-R) which regulates release of gastrointestinal hormones, smooth muscle contraction and proliferation of epithelial as well as cancer cells. The GRP-R is a G-protein coupled receptor (GPCR) which activates phospholipase C signaling pathways. The GRP-R is expressed in numerous cancers including breast, colon, lung and prostate cancer.
Subject: Chromosome X; Signal Membrane receptor; Genes Section
Publisher: Jean-Loup Huret (Editor-in-Chief) ; INIST-CNRS (Publisher)
Date: 2014

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