Measurement of the mechanical properties of alginate beads using ultrasounds

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URI: http://hdl.handle.net/2042/36663
Title: Measurement of the mechanical properties of alginate beads using ultrasounds
Author: SALSAC, Anne-Virginie; ZHANG, Liguo; GHERBEZZA, Jean-Marc
Description: Alginate beads are one of the most common vehicles for encapsulation. When designing bioartificial organs, they are used as matrix for cell culture. Cell survival and activity depend essentially on the bead physical and mechanical properties. In this study, the mechanical properties of millimetric beads are evaluated using an ultrasound technique. We study the effects that the concentration in alginate has on the elastic properties of the beads. We show that density and stiffness coefficient of the bead are not independent. A measurement of the density can therefore provide a good estimation of the stiffness coefficient.
Publisher: AFM, Maison de la Mécanique, 39/41 rue Louis Blanc - 92400 Courbevoie
Date: 2009

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